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Hydromorphone can be addictive if misused, with abuse also carrying a high risk for adverse effects like sedation, respiratory depression, and overdose Loss of life.Generally, lengthy-time period use is barely advisable for pain as a result of most cancers. It might be used by mouth or by injection right into a vein, muscle, or underneath the skin.

Serotonin Syndrome: Severe reactions are achievable when hydromorphone is combined with other drugs that act on serotonin, for example tricyclic antidepressants and serotonin reuptake inhibitors, medicines applied to treat melancholy. Signs of the response might consist of muscle mass rigidity and spasms, issue shifting, improvements in mental poin